Helminthic Therapy wiki - Recent changes [en]

Helminthic therapy personal stories

John — Wed, 20 May 2026 08:33:32 GMT

Crohn's disease

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	=== Crohn's disease ===		=== Crohn's disease ===
	~~Also see~~ [[Helminthic therapy and inflammatory bowel disease (IBD) \| '''Helminthic therapy and inflammatory bowel disease (IBD)''']].		See [[Helminthic therapy and inflammatory bowel disease (IBD) \| '''Helminthic therapy and inflammatory bowel disease (IBD)''']].

	The first eight reports are more detailed than the quotes that follow them.		The first eight reports are more detailed than the quotes that follow them.
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	* "Have Crohns and was in hospital with 600+ calprotectin and 60+ CRP (ten months ago). After 15 doses of TSO am off all meds and CRP is <1 and calprotectin normal. I have 5 more doses left but transitioning to NA because it's cheaper. Just took 10 NA." [https://www.facebook.com/groups/htsupport/posts/24264812243148069/]<!--MP-->		* "Have Crohns and was in hospital with 600+ calprotectin and 60+ CRP (ten months ago). After 15 doses of TSO am off all meds and CRP is <1 and calprotectin normal. I have 5 more doses left but transitioning to NA because it's cheaper. Just took 10 NA." [https://www.facebook.com/groups/htsupport/posts/24264812243148069/]<!--MP-->

			* "I have watched my child's Crohn's Disease improve vastly since beginning HDCs. He had no quality of life, prior." [https://www.facebook.com/groups/htsupport/posts/26709369068692362/?comment_id=26712024695093466] <!--KO-->

	=== Dandruff ===		=== Dandruff ===

Helminthic therapy and neuropsychiatric disorders

Jlm — Wed, 20 May 2026 07:46:04 GMT

Autoimmune encephalitis

← Older revision		Revision as of 07:46, 20 May 2026
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	Autoimmune encephalitis can result from a number of autoimmune diseases including: Rasmussen encephalitis, Systemic lupus erythematosus, Behçet's disease, Hashimoto's encephalopathy, Autoimmune limbic encephalitis and Sydenham's chorea.		Autoimmune encephalitis can result from a number of autoimmune diseases including: Rasmussen encephalitis, Systemic lupus erythematosus, Behçet's disease, Hashimoto's encephalopathy, Autoimmune limbic encephalitis and Sydenham's chorea.

	See above Autoimmune pathways		See above The scientific evidence : Autoimmune pathways

	== Bipolar disorder ==		== Bipolar disorder ==

Helminthic therapy and autoimmune diseases

Jlm — Wed, 20 May 2026 07:45:42 GMT

Autoimmune encephalitis

← Older revision		Revision as of 07:45, 20 May 2026
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	[https://en.wikipedia.org/wiki/Autoimmune_encephalitis Autoimmune encephalitis (AIE)] is one of the most common causes of noninfectious encephalitis.		[https://en.wikipedia.org/wiki/Autoimmune_encephalitis Autoimmune encephalitis (AIE)] is one of the most common causes of noninfectious encephalitis.

	Autoimmune encephalitis can result from a number of autoimmune diseases including: Rasmussen encephalitis, Systemic lupus erythematosus, Behçet's disease, Hashimoto's encephalopathy, Autoimmune limbic encephalitis and Sydenham's chorea. See:		Autoimmune encephalitis can result from a number of autoimmune diseases including: Rasmussen encephalitis, Systemic lupus erythematosus, Behçet's disease, Hashimoto's encephalopathy, Autoimmune limbic encephalitis and Sydenham's chorea.
	* 2021 Jun 17 [~~https~~:~~//pubmed.ncbi.nlm.nih.gov/34220839/ Short- and Long-Lived Autoantibody-Secreting Cells in~~ Autoimmune ~~Neurological Disorders~~]
			See [[Helminthic therapy and neuropsychiatric disorders#Autoimmune encephalitis \| '''Helminthic therapy and neuropsychiatric disorders: Autoimmune encephalitis''']]

	== Autoimmune kidney diseases ==		== Autoimmune kidney diseases ==

Helminthic therapy and neuropsychiatric disorders

Jlm — Wed, 20 May 2026 07:44:35 GMT

Tourette Syndrome

Show changes

Helminthic therapy and neurodevelopmental disorders

Jlm — Wed, 20 May 2026 07:15:59 GMT

Scientific papers

← Older revision		Revision as of 07:15, 20 May 2026
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	* ✅ 2024 Oct 22 [https://pubmed.ncbi.nlm.nih.gov/39321022/ The rebalancing of the immune system at the maternal-fetal interface ameliorates autism-like behavior in adult offspring] -- [https://www.cell.com/cell-reports/fulltext/S2211-1247(24)01138-0?uuid=uuid%3A03bd97aa-0f2e-49d6-ad75-0982b8d5be9a Full text]		* ✅ 2024 Oct 22 [https://pubmed.ncbi.nlm.nih.gov/39321022/ The rebalancing of the immune system at the maternal-fetal interface ameliorates autism-like behavior in adult offspring] -- [https://www.cell.com/cell-reports/fulltext/S2211-1247(24)01138-0?uuid=uuid%3A03bd97aa-0f2e-49d6-ad75-0982b8d5be9a Full text]
	* 2024 Jun [https://escholarship.mcgill.ca/concern/theses/5x21tn216 Maternal gastrointestinal nematode infection alters hippocampal neuroimmunity, enhances long-term potentiation and spatial memory and improves resistance to direct infection in mouse offspring] -- [https://escholarship.mcgill.ca/downloads/5138jm21w?locale=en PDF] (Thesis)		* 2024 Jun [https://escholarship.mcgill.ca/concern/theses/5x21tn216 Maternal gastrointestinal nematode infection alters hippocampal neuroimmunity, enhances long-term potentiation and spatial memory and improves resistance to direct infection in mouse offspring] -- [https://escholarship.mcgill.ca/downloads/5138jm21w?locale=en PDF] (Thesis)
	* 2024 Jun [https://pubmed.ncbi.nlm.nih.gov/38808523/ Gastrointestinal nematode infection during pregnancy and lactation enhances spatial reference memory and reduces indicators of anxiety-like behaviour in uninfected adult female mouse offspring~~] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC11474017/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC11474017/pdf/S0031182024000696a.pdf PDF~~]		* 2024 Jun [https://pubmed.ncbi.nlm.nih.gov/38808523/ Gastrointestinal nematode infection during pregnancy and lactation enhances spatial reference memory and reduces indicators of anxiety-like behaviour in uninfected adult female mouse offspring]
	* 2024 May 10 [https://pubmed.ncbi.nlm.nih.gov/38730262/ Maternal gastrointestinal nematode infection alters hippocampal neuroimmunity, promotes synaptic plasticity, and improves resistance to direct infection in offspring] -- [https://~~pmc~~.ncbi.nlm.nih.gov/~~articles~~/~~PMC11087533/ Full text] \| [https~~:~~//pmc.ncbi.nlm.nih.gov/articles/PMC11087533/pdf/41598_2024_Article_60865.pdf PDF~~]		* 2024 May 10 [https://pubmed.ncbi.nlm.nih.gov/38730262/ Maternal gastrointestinal nematode infection alters hippocampal neuroimmunity, promotes synaptic plasticity, and improves resistance to direct infection in offspring]
			* 2024 Feb 16 [https://pubmed.ncbi.nlm.nih.gov/38398873/ Between Dysbiosis, Maternal Immune Activation and Autism: Is There a Common Pathway?]
	* 2022 Jun 13 [https://pubmed.ncbi.nlm.nih.gov/35697723/ Maternal gastrointestinal nematode infection enhances spatial memory of uninfected juvenile mouse pups] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC9192650/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC9192650/pdf/41598_2022_Article_13971.pdf PDF]		* 2022 Jun 13 [https://pubmed.ncbi.nlm.nih.gov/35697723/ Maternal gastrointestinal nematode infection enhances spatial memory of uninfected juvenile mouse pups] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC9192650/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC9192650/pdf/41598_2022_Article_13971.pdf PDF]
	* 2021 Nov 11 [https://pubmed.ncbi.nlm.nih.gov/34764345/ Maternal nematode infection upregulates expression of Th2/Treg and diapedesis related genes in the neonatal brain]		* 2021 Nov 11 [https://pubmed.ncbi.nlm.nih.gov/34764345/ Maternal nematode infection upregulates expression of Th2/Treg and diapedesis related genes in the neonatal brain]
	* 2021 Jan [https://escholarship.mcgill.ca/concern/theses/k643b593k?locale=en Upregulated Th2/treg brain gene expression in pups of nematode-infected mice associated with enhanced expression of leukocyte trans-endothelial cell migration across the blood brain barrier] -- [https://escholarship.mcgill.ca/downloads/wm117t47f?locale=en PDF] (Thesis)		* 2021 Jan [https://escholarship.mcgill.ca/concern/theses/k643b593k?locale=en Upregulated Th2/treg brain gene expression in pups of nematode-infected mice associated with enhanced expression of leukocyte trans-endothelial cell migration across the blood brain barrier] -- [https://escholarship.mcgill.ca/downloads/wm117t47f?locale=en PDF] (Thesis, McGill)
	* 2020 Sep [https://escholarship.mcgill.ca/concern/theses/0k225g67s Maternal nematode infection alters neonatal brain gene expression and maternal and neonatal microbiomes] -- [https://~~escholarship~~.~~mcgill~~.ca/~~downloads~~/~~8336h626k?locale=en PDF~~] ~~(Thesis)~~		* 2020 Sep [https://escholarship.mcgill.ca/concern/theses/0k225g67s Maternal nematode infection alters neonatal brain gene expression and maternal and neonatal microbiomes] (Thesis, McGill)
			* 2019 Apr [https://www.ncbi.nlm.nih.gov/pubmed/30902137 Helminth therapy for autism under gut-brain axis- hypothesis]
	* 2019 Mar 12 [https://pubmed.ncbi.nlm.nih.gov/30862816/ Maternal Gastrointestinal Nematode Infection Up-regulates Expression of Genes Associated with Long-Term Potentiation in Perinatal Brains of Uninfected Developing Pups]		* 2019 Mar 12 [https://pubmed.ncbi.nlm.nih.gov/30862816/ Maternal Gastrointestinal Nematode Infection Up-regulates Expression of Genes Associated with Long-Term Potentiation in Perinatal Brains of Uninfected Developing Pups]
	:{{Quote\|indent}}in seven-day old pups, long-term potentiation and four related pathways essential for the development of synaptic plasticity, cognition and memory were up-regulated{{Quote\|/indent}}		:{{Quote\|indent}}in seven-day old pups, long-term potentiation and four related pathways essential for the development of synaptic plasticity, cognition and memory were up-regulated{{Quote\|/indent}}
	* 2018 Sep 25 [https://pubmed.ncbi.nlm.nih.gov/30254300/ Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats]		* 2018 Sep 25 [https://pubmed.ncbi.nlm.nih.gov/30254300/ Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats]
			* 2018 Jun 4 [https://www.mdpi.com/1424-8247/11/2/56/htm Inflammation and Neuro-Immune Dysregulations in Autism Spectrum Disorders]
			* 2018 Mar 7 [https://pubmed.ncbi.nlm.nih.gov/29563885/ Interplay Between Peripheral and Central Inflammation in Autism Spectrum Disorders]
			* 2017 May [http://www.ncbi.nlm.nih.gov/pubmed/27240605 Practices and outcomes of self-treatment with helminths based on physicians' observations] \| [https://mywikis-eu-wiki-media.s3.eu-central-2.wasabisys.com/htwiki/Practices_and_outcomes_of_self-treatment_with_helminths_based_on_physicians_observations.pdf PDF]
			* 2016 May [https://www.sciencedirect.com/science/article/abs/pii/S0924977X15001935 Trichuris Suis Ova (TSO) as an immune-inflammatory treatment for repetitive behaviors in autism spectrum disorders (ASD)]
			* 2016 Jan 20 [https://www.youtube.com/watch?v=M9M6hqaMz98&t=33s Autism & Helminths: The Good, the Bad, and the Rumors] (Autism Research Institute, YouTube)
	* 2016 Jan [https://pubmed.ncbi.nlm.nih.gov/26162711 Got Worms? Perinatal Exposure to Helminths Prevents Persistent Immune Sensitization and Cognitive Dysfunction Induced by Early-Life Infection] -- [https://laurenlwilliamson.com/wp-content/uploads/2021/01/williamson-et-al-2016-helminths.pdf pdf] (see also [https://sicb.org/the-old-friends-hypothesis-reopening-a-can-of-worms/ The “Old Friends” hypothesis: Reopening a can of worms])		* 2016 Jan [https://pubmed.ncbi.nlm.nih.gov/26162711 Got Worms? Perinatal Exposure to Helminths Prevents Persistent Immune Sensitization and Cognitive Dysfunction Induced by Early-Life Infection] -- [https://laurenlwilliamson.com/wp-content/uploads/2021/01/williamson-et-al-2016-helminths.pdf pdf] (see also [https://sicb.org/the-old-friends-hypothesis-reopening-a-can-of-worms/ The “Old Friends” hypothesis: Reopening a can of worms])
			* 2016 [https://www.ncbi.nlm.nih.gov/pubmed/27592717 Enteric Ecosystem Disruption in Autism Spectrum Disorder: Can the Microbiota and Macrobiota be Restored?]
			* 2016 [https://www.autism.org/helminths-as-a-cause-or-a-potential-treatment-for-autism/ Helminths as a Cause or a Potential Treatment for Autism?] (Autism Research Institute)
			* 2015 May 11 [https://www.facebook.com/tanawisa/posts/746878402097165 Comments on TSO for Autism from a European Biomedical Center for Autism Research]
			* 2015 May 7 [http://www.ncbi.nlm.nih.gov/pubmed/25956237 Approaches to studying and manipulating the enteric microbiome to improve autism symptoms] -- [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425814/ Full text] \| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425814/pdf/MEHD-26-26878.pdf PDF]
			* 2015 May 6 [https://www.youtube.com/watch?v=yGqTPM10wrY Microbiome Research in Autism Spectrum Disorders] (Autism Research Institute, YouTube)
			* 2015 Jan 28 [http://www.ncbi.nlm.nih.gov/pubmed/25634608 A model for the induction of autism in the ecosystem of the human body: the anatomy of a modern pandemic?] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC4310853/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC4310853/pdf/MEHD-26-26253.pdf PDF]
			* 2013 Dec 12 [http://globenewswire.com/news-release/2013/12/12/596603/10061345/en/Coronado-Biosciences-Announces-Presentation-of-Interim-Data-From-Autism-Study-at-Neuropsychopharmacology-Meeting.html Presentation of Interim Data From Autism Study at Neuropsychopharmacology Meeting]
			* 2013 Jul [http://www.ncbi.nlm.nih.gov/pubmed/23597946 Possible use of Trichuris suis ova in autism spectrum disorders therapy]
			* 2012 Jun 26 [http://www.ncbi.nlm.nih.gov/pubmed/22928103 Is autism a member of a family of diseases resulting from genetic/cultural mismatches? Implications for treatment and prevention] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC3420574/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC3420574/ PDF]
			* ⚡ 2010 Oct 13 [https://evmedreview.com/reconstituting-the-depleted-biome-to-prevent-immune-disorders/ Reconstituting the depleted biome to prevent immune disorders] William Parker, Duke University. Explains why replacing absent "old friends" may be the only reasonable therapy for a wide range of immune-associated disorders, including allergy, autoimmunity and autism.
			* 2007 [http://www.ncbi.nlm.nih.gov/pubmed/17412520 Autism, asthma, inflammation, and the hygiene hypothesis] -- [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048743/ Full text] \| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048743/pdf/nihms-29963.pdf PDF]
			* 2004 Jun [https://www.ncbi.nlm.nih.gov/pubmed/15330453 A review of autism and the immune response] -- [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270714/pdf/CDI-11-165.pdf PDF]

	For more papers, see		For more papers, see
	* [[Helminthic therapy and autism \| '''Helminthic therapy and autism''']]
	* [[Mechanisms underlying helminth colonization#Maternal Protection \| '''Mechanisms underlying helminth colonization: Maternal Protection''']]		* [[Mechanisms underlying helminth colonization#Maternal Protection \| '''Mechanisms underlying helminth colonization: Maternal Protection''']]

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	* 2026 Feb 1 [https://pubmed.ncbi.nlm.nih.gov/41646391/ Sex specific effects of adoptive Tregs transfer on the brain and periphery in maternal immune activation offspring rescuing immune dysregulation] (Preprint)		* 2026 Feb 1 [https://pubmed.ncbi.nlm.nih.gov/41646391/ Sex specific effects of adoptive Tregs transfer on the brain and periphery in maternal immune activation offspring rescuing immune dysregulation] (Preprint)
	* 2026 Feb [https://pubmed.ncbi.nlm.nih.gov/41344579/ Maternal immune activation during gestation modulates offspring immune profiles in a nonhuman primate model]		* 2026 Feb [https://pubmed.ncbi.nlm.nih.gov/41344579/ Maternal immune activation during gestation modulates offspring immune profiles in a nonhuman primate model]
			{{Expando\|More papers (Tap to expand / minimize)}}
	* 2026 Jan 24 [https://pubmed.ncbi.nlm.nih.gov/41750127/ Maternal Poly (I:C)-Induced Placental Inflammation and Endocrine Dysfunction Are Associated with Disrupted Corticogenesis in Mouse Offspring]		* 2026 Jan 24 [https://pubmed.ncbi.nlm.nih.gov/41750127/ Maternal Poly (I:C)-Induced Placental Inflammation and Endocrine Dysfunction Are Associated with Disrupted Corticogenesis in Mouse Offspring]
	* 2026 Jan 3 [https://pubmed.ncbi.nlm.nih.gov/41484215/ Prenatal Interferon-Alpha Exposure Induces Autism-Like Neurobehavioral and Neurochemical Alterations in Male Offspring]		* 2026 Jan 3 [https://pubmed.ncbi.nlm.nih.gov/41484215/ Prenatal Interferon-Alpha Exposure Induces Autism-Like Neurobehavioral and Neurochemical Alterations in Male Offspring]
	* 2025 Nov 24 [https://pubmed.ncbi.nlm.nih.gov/41322658/ Maternal Immune Activation and Neurodevelopmental Disorders: Integrating Molecular, Cellular and Systems Mechanisms] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC12661954/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC12661954/pdf/ndt-21-2575.pdf PDF]		* 2025 Nov 24 [https://pubmed.ncbi.nlm.nih.gov/41322658/ Maternal Immune Activation and Neurodevelopmental Disorders: Integrating Molecular, Cellular and Systems Mechanisms] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC12661954/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC12661954/pdf/ndt-21-2575.pdf PDF]
	~~{{Expando\|More papers (Tap to expand / minimize)}}~~
	* 2025 Nov 16 [https://pubmed.ncbi.nlm.nih.gov/41258036/ Double-hit of MIA and Nod2 deficiency induces sex-specific offspring behavioral abnormalities through placental dysregulation]		* 2025 Nov 16 [https://pubmed.ncbi.nlm.nih.gov/41258036/ Double-hit of MIA and Nod2 deficiency induces sex-specific offspring behavioral abnormalities through placental dysregulation]
	* 2025 Oct 16 [https://pubmed.ncbi.nlm.nih.gov/41150800/ IL-6 Inhibition Partially Ameliorates Maternal Immune Activation-Induced Autism-Like Behavioral Abnormalities in Mice]		* 2025 Oct 16 [https://pubmed.ncbi.nlm.nih.gov/41150800/ IL-6 Inhibition Partially Ameliorates Maternal Immune Activation-Induced Autism-Like Behavioral Abnormalities in Mice]
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	* 2016 Jan 13 [https://pubmed.ncbi.nlm.nih.gov/26757726/ Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines]		* 2016 Jan 13 [https://pubmed.ncbi.nlm.nih.gov/26757726/ Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines]

	==== Mast cells ===		==== Mast cells ====

	* 2025 Sep [https://pubmed.ncbi.nlm.nih.gov/40523550/ The role of mast cells in Autism Spectrum Disorder]		* 2025 Sep [https://pubmed.ncbi.nlm.nih.gov/40523550/ The role of mast cells in Autism Spectrum Disorder]

Helminthic therapy and autism

Jlm — Wed, 20 May 2026 06:54:07 GMT

The science on helminthic therapy and autism: transfer see also in Helminthic therapy and neurodevelopmental disorders

← Older revision		Revision as of 06:54, 20 May 2026
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	'''See also''':		'''See also''':

	* 2026 May [https://pubmed.ncbi.nlm.nih.gov/42138450/ Unveiling the Molecular Mechanism of Intestinal Metabolite para-Cresol in Modulating Neuroinflammation and Synaptic Dysfunction: Implications for Autism Spectrum Disorder]
	* 2026 Mar 12 [https://pubmed.ncbi.nlm.nih.gov/41818176/ Translocation of bacteria from the gut to the brain in mice] (Media coverage Psypost [https://www.psypost.org/scientists-just-discovered-that-a-high-fat-diet-can-cause-gut-bacteria-to-enter-the-brain/ Scientists just discovered that a high-fat diet can cause gut bacteria to enter the brain])
	* 2026 Feb 24 [https://pubmed.ncbi.nlm.nih.gov/41742408/ Endogenous retrovirus-derived RNA-DNA hybrids induce microglial synaptic pruning in autism models]
	* 2026 Feb 15 [https://pubmed.ncbi.nlm.nih.gov/41539110/ Gut virome plays an extended role with bacteriome in neurological health and disease] (also [https://doi.org/10.22541/au.175983852.28276315/v1 preprint])
	* 2026 Jan 3 [https://pubmed.ncbi.nlm.nih.gov/41484215/ Prenatal Interferon-Alpha Exposure Induces Autism-Like Neurobehavioral and Neurochemical Alterations in Male Offspring]
	* 2025 Nov 29 [https://pubmed.ncbi.nlm.nih.gov/41317234/ The Gut-Brain Axis in Autism: Inflammatory Mechanisms, Molecular Insights, and Emerging Microbiome-Based Therapies]
	* 2025 Nov 10 [https://pubmed.ncbi.nlm.nih.gov/41305374/ Gut Microbiotas, Plasma Metabolites, and Autism Spectrum Disorder: A Bidirectional Mendelian Randomization Analysis] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC12655273/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC12655273/pdf/pathogens-14-01137.pdf PDF]
	* 2025 Oct 16 [https://pubmed.ncbi.nlm.nih.gov/41150800/ IL-6 Inhibition Partially Ameliorates Maternal Immune Activation-Induced Autism-Like Behavioral Abnormalities in Mice]
	* 2025 Oct 1 [https://pubmed.ncbi.nlm.nih.gov/40505847/ Gut microbiota and behavioral ontogeny in autism spectrum disorder: a pathway to therapeutic innovations]
	* 2025 Sep 13 [https://pubmed.ncbi.nlm.nih.gov/41009500/ Altered Gut Microbial Diversity and Depletion of SCFA-Producing Taxa Associated with ASD-like Phenotypes in a Prenatal VPA Rat Model] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC12469871/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC12469871/pdf/ijms-26-08931.pdf PDF]
	* 2025 Sep [https://pubmed.ncbi.nlm.nih.gov/40523550/ The role of mast cells in Autism Spectrum Disorder] -- [https://www.sciencedirect.com/science/article/pii/S0149763425002647?via%3Dihub Full text]
	* 2025 May 21 [https://pubmed.ncbi.nlm.nih.gov/40400531/ Causal relationship between gut microbiota, blood metabolites and autism spectrum disorder: a Mendelian randomization study] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC12092132/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC12092132/pdf/rsos.250158.pdf PDF]
	* 2025 Mar 25 [https://pubmed.ncbi.nlm.nih.gov/40218893/ The Gut-Brain-Microbiota Connection and Its Role in Autism Spectrum Disorders] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC11990867/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC11990867/pdf/nutrients-17-01135.pdf PDF]
	* 2025 Jan [https://pubmed.ncbi.nlm.nih.gov/39733842/ IUPHAR review: Targeted therapies of signaling pathways based on the gut microbiome in autism spectrum disorders: Mechanistic and therapeutic applications]
	* 2024 Dec [https://pubmed.ncbi.nlm.nih.gov/39580060/ Potential key pathophysiological participant and treatment target in autism spectrum disorder: Microglia]
	* 2024 Nov 15 [https://pubmed.ncbi.nlm.nih.gov/39461606/ Investigating brain-gut microbiota dynamics and inflammatory processes in an autistic-like rat model using MRI biomarkers during childhood and adolescence] -- [https://www.sciencedirect.com/science/article/pii/S1053811924003963?via%3Dihub Full text]
	* 2024 Sep 16 [https://pubmed.ncbi.nlm.nih.gov/39328398/ Gut microbiota of children with autism spectrum disorder and healthy siblings: A comparative study]
	* 2024 Feb 24 [https://pubmed.ncbi.nlm.nih.gov/38473898/ Mast Cells in Autism Spectrum Disorder-The Enigma to Be Solved?] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC10932299/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC10932299/pdf/ijms-25-02651.pdf PDF]
	* 2024 Jan-Dec [https://pubmed.ncbi.nlm.nih.gov/39120056/ The early life exposome and autism risk: a role for the maternal microbiome?]
	* 2023 Dec 16 [https://pubmed.ncbi.nlm.nih.gov/38104181/ Abnormal neutrophil-to-lymphocyte ratio in children with autism spectrum disorder and history of maternal immune activation]
	* 2023 Feb [https://pubmed.ncbi.nlm.nih.gov/36494048/ Innate immune dysfunction and neuroinflammation in autism spectrum disorder (ASD)]
	* 2022 Nov 30 [https://pubmed.ncbi.nlm.nih.gov/36300375/ Systemic maternal inflammation promotes ASD via IL-6 and IFN-γ]
	* 2022 Jun 3 [https://pubmed.ncbi.nlm.nih.gov/35721203/ The Endocannabinoids-Microbiota Partnership in Gut-Brain Axis Homeostasis: Implications for Autism Spectrum Disorders] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC9204215/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC9204215/pdf/fphar-13-869606.pdf] (linked to [[Mechanisms underlying helminth colonization##Endocannabinoids \| this articles]])
	* 2019 Dec 14 [https://pubmed.ncbi.nlm.nih.gov/31837704/ Maternal elevated salt consumption and the development of autism spectrum disorder in the offspring]
	* 2016 Jan 13 [https://pubmed.ncbi.nlm.nih.gov/26757726/ Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC4711034/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC4711034/pdf/12974_2015_Article_463.pdf PDF]

	For more research, use your device's search function (the 'Command' and 'F' keys on a desktop or laptop, or 'Find in page' in the drop-down menu from the three dots icon on a mobile) to search the following page for "autism" and "ASD".

	* [[Helminthic therapy research \| '''Helminthic therapy research''']]		* [[Helminthic therapy research \| '''Helminthic therapy research''']]

Helminthic therapy and neurodevelopmental disorders

Jlm — Wed, 20 May 2026 06:53:41 GMT

Scientific papers not directly related

Show changes

Helminthic therapy and autism

Jlm — Wed, 20 May 2026 06:32:33 GMT

The science on helminthic therapy and autism

← Older revision		Revision as of 06:32, 20 May 2026
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	'''See also''':		'''See also''':

			* 2026 May [https://pubmed.ncbi.nlm.nih.gov/42138450/ Unveiling the Molecular Mechanism of Intestinal Metabolite para-Cresol in Modulating Neuroinflammation and Synaptic Dysfunction: Implications for Autism Spectrum Disorder]
	* 2026 Mar 12 [https://pubmed.ncbi.nlm.nih.gov/41818176/ Translocation of bacteria from the gut to the brain in mice] (Media coverage Psypost [https://www.psypost.org/scientists-just-discovered-that-a-high-fat-diet-can-cause-gut-bacteria-to-enter-the-brain/ Scientists just discovered that a high-fat diet can cause gut bacteria to enter the brain])		* 2026 Mar 12 [https://pubmed.ncbi.nlm.nih.gov/41818176/ Translocation of bacteria from the gut to the brain in mice] (Media coverage Psypost [https://www.psypost.org/scientists-just-discovered-that-a-high-fat-diet-can-cause-gut-bacteria-to-enter-the-brain/ Scientists just discovered that a high-fat diet can cause gut bacteria to enter the brain])
	* 2026 Feb 24 [https://pubmed.ncbi.nlm.nih.gov/41742408/ Endogenous retrovirus-derived RNA-DNA hybrids induce microglial synaptic pruning in autism models]		* 2026 Feb 24 [https://pubmed.ncbi.nlm.nih.gov/41742408/ Endogenous retrovirus-derived RNA-DNA hybrids induce microglial synaptic pruning in autism models]

Helminthic therapy and neurodevelopmental disorders

Jlm — Wed, 20 May 2026 06:32:25 GMT

Microbiota Gut-Brain Axis

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	==== Microbiota Gut-Brain Axis ====		==== Microbiota Gut-Brain Axis ====

			* 2026 May [https://pubmed.ncbi.nlm.nih.gov/42138450/ Unveiling the Molecular Mechanism of Intestinal Metabolite para-Cresol in Modulating Neuroinflammation and Synaptic Dysfunction: Implications for Autism Spectrum Disorder]
	* 2026 Feb 15 [https://pubmed.ncbi.nlm.nih.gov/41539110/ Gut virome plays an extended role with bacteriome in neurological health and disease] (also [https://doi.org/10.22541/au.175983852.28276315/v1 preprint])		* 2026 Feb 15 [https://pubmed.ncbi.nlm.nih.gov/41539110/ Gut virome plays an extended role with bacteriome in neurological health and disease] (also [https://doi.org/10.22541/au.175983852.28276315/v1 preprint])
	* 2026 Jan 23 [https://pubmed.ncbi.nlm.nih.gov/41577801/ Intergenerational effects of the microbiota on neurodevelopment: mechanisms and therapeutic perspectives]		* 2026 Jan 23 [https://pubmed.ncbi.nlm.nih.gov/41577801/ Intergenerational effects of the microbiota on neurodevelopment: mechanisms and therapeutic perspectives]

Helminthic therapy and autism

Jlm — Wed, 20 May 2026 06:30:14 GMT

The science on helminthic therapy and autism

← Older revision		Revision as of 06:30, 20 May 2026
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	* 2025 Mar 25 [https://pubmed.ncbi.nlm.nih.gov/40218893/ The Gut-Brain-Microbiota Connection and Its Role in Autism Spectrum Disorders] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC11990867/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC11990867/pdf/nutrients-17-01135.pdf PDF]		* 2025 Mar 25 [https://pubmed.ncbi.nlm.nih.gov/40218893/ The Gut-Brain-Microbiota Connection and Its Role in Autism Spectrum Disorders] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC11990867/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC11990867/pdf/nutrients-17-01135.pdf PDF]
	* 2025 Jan [https://pubmed.ncbi.nlm.nih.gov/39733842/ IUPHAR review: Targeted therapies of signaling pathways based on the gut microbiome in autism spectrum disorders: Mechanistic and therapeutic applications]		* 2025 Jan [https://pubmed.ncbi.nlm.nih.gov/39733842/ IUPHAR review: Targeted therapies of signaling pathways based on the gut microbiome in autism spectrum disorders: Mechanistic and therapeutic applications]
			* 2024 Dec [https://pubmed.ncbi.nlm.nih.gov/39580060/ Potential key pathophysiological participant and treatment target in autism spectrum disorder: Microglia]
	* 2024 Nov 15 [https://pubmed.ncbi.nlm.nih.gov/39461606/ Investigating brain-gut microbiota dynamics and inflammatory processes in an autistic-like rat model using MRI biomarkers during childhood and adolescence] -- [https://www.sciencedirect.com/science/article/pii/S1053811924003963?via%3Dihub Full text]		* 2024 Nov 15 [https://pubmed.ncbi.nlm.nih.gov/39461606/ Investigating brain-gut microbiota dynamics and inflammatory processes in an autistic-like rat model using MRI biomarkers during childhood and adolescence] -- [https://www.sciencedirect.com/science/article/pii/S1053811924003963?via%3Dihub Full text]
	* 2024 Sep 16 [https://pubmed.ncbi.nlm.nih.gov/39328398/ Gut microbiota of children with autism spectrum disorder and healthy siblings: A comparative study]		* 2024 Sep 16 [https://pubmed.ncbi.nlm.nih.gov/39328398/ Gut microbiota of children with autism spectrum disorder and healthy siblings: A comparative study]
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	* 2024 Jan-Dec [https://pubmed.ncbi.nlm.nih.gov/39120056/ The early life exposome and autism risk: a role for the maternal microbiome?]		* 2024 Jan-Dec [https://pubmed.ncbi.nlm.nih.gov/39120056/ The early life exposome and autism risk: a role for the maternal microbiome?]
	* 2023 Dec 16 [https://pubmed.ncbi.nlm.nih.gov/38104181/ Abnormal neutrophil-to-lymphocyte ratio in children with autism spectrum disorder and history of maternal immune activation]		* 2023 Dec 16 [https://pubmed.ncbi.nlm.nih.gov/38104181/ Abnormal neutrophil-to-lymphocyte ratio in children with autism spectrum disorder and history of maternal immune activation]
			* 2023 Feb [https://pubmed.ncbi.nlm.nih.gov/36494048/ Innate immune dysfunction and neuroinflammation in autism spectrum disorder (ASD)]
	* 2022 Nov 30 [https://pubmed.ncbi.nlm.nih.gov/36300375/ Systemic maternal inflammation promotes ASD via IL-6 and IFN-γ]		* 2022 Nov 30 [https://pubmed.ncbi.nlm.nih.gov/36300375/ Systemic maternal inflammation promotes ASD via IL-6 and IFN-γ]
	* 2022 Jun 3 [https://pubmed.ncbi.nlm.nih.gov/35721203/ The Endocannabinoids-Microbiota Partnership in Gut-Brain Axis Homeostasis: Implications for Autism Spectrum Disorders] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC9204215/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC9204215/pdf/fphar-13-869606.pdf] (linked to [[Mechanisms underlying helminth colonization##Endocannabinoids \| this articles]])		* 2022 Jun 3 [https://pubmed.ncbi.nlm.nih.gov/35721203/ The Endocannabinoids-Microbiota Partnership in Gut-Brain Axis Homeostasis: Implications for Autism Spectrum Disorders] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC9204215/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC9204215/pdf/fphar-13-869606.pdf] (linked to [[Mechanisms underlying helminth colonization##Endocannabinoids \| this articles]])

Helminthic therapy and neurodevelopmental disorders

Jlm — Wed, 20 May 2026 06:25:16 GMT

Maternal immune activation

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	==== Maternal immune activation ====		==== Maternal immune activation ====

			* 2026 Feb 24 [https://pubmed.ncbi.nlm.nih.gov/41742408/ Endogenous retrovirus-derived RNA-DNA hybrids induce microglial synaptic pruning in autism models]
			* 2026 Feb 19 [https://pubmed.ncbi.nlm.nih.gov/41742408/ Microglial Lyn Kinase-TRPV4 axis mediates social deficits in a maternal immune activation model]
	* 2026 Feb 3 [https://pubmed.ncbi.nlm.nih.gov/41676570/ Maternal-fetal immune conflict contributes to male-specific impairments in a mouse model of neurodevelopmental disorders] (Preprint)		* 2026 Feb 3 [https://pubmed.ncbi.nlm.nih.gov/41676570/ Maternal-fetal immune conflict contributes to male-specific impairments in a mouse model of neurodevelopmental disorders] (Preprint)
	* 2026 Feb 1 [https://pubmed.ncbi.nlm.nih.gov/41646391/ Sex specific effects of adoptive Tregs transfer on the brain and periphery in maternal immune activation offspring rescuing immune dysregulation] (Preprint)		* 2026 Feb 1 [https://pubmed.ncbi.nlm.nih.gov/41646391/ Sex specific effects of adoptive Tregs transfer on the brain and periphery in maternal immune activation offspring rescuing immune dysregulation] (Preprint)

Helminthic therapy and autism

Jlm — Wed, 20 May 2026 06:22:57 GMT

The science on helminthic therapy and autism

← Older revision		Revision as of 06:22, 20 May 2026
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	* 2026 Mar 12 [https://pubmed.ncbi.nlm.nih.gov/41818176/ Translocation of bacteria from the gut to the brain in mice] (Media coverage Psypost [https://www.psypost.org/scientists-just-discovered-that-a-high-fat-diet-can-cause-gut-bacteria-to-enter-the-brain/ Scientists just discovered that a high-fat diet can cause gut bacteria to enter the brain])		* 2026 Mar 12 [https://pubmed.ncbi.nlm.nih.gov/41818176/ Translocation of bacteria from the gut to the brain in mice] (Media coverage Psypost [https://www.psypost.org/scientists-just-discovered-that-a-high-fat-diet-can-cause-gut-bacteria-to-enter-the-brain/ Scientists just discovered that a high-fat diet can cause gut bacteria to enter the brain])
			* 2026 Feb 24 [https://pubmed.ncbi.nlm.nih.gov/41742408/ Endogenous retrovirus-derived RNA-DNA hybrids induce microglial synaptic pruning in autism models]
	* 2026 Feb 15 [https://pubmed.ncbi.nlm.nih.gov/41539110/ Gut virome plays an extended role with bacteriome in neurological health and disease] (also [https://doi.org/10.22541/au.175983852.28276315/v1 preprint])		* 2026 Feb 15 [https://pubmed.ncbi.nlm.nih.gov/41539110/ Gut virome plays an extended role with bacteriome in neurological health and disease] (also [https://doi.org/10.22541/au.175983852.28276315/v1 preprint])
	* 2026 Jan 3 [https://pubmed.ncbi.nlm.nih.gov/41484215/ Prenatal Interferon-Alpha Exposure Induces Autism-Like Neurobehavioral and Neurochemical Alterations in Male Offspring]		* 2026 Jan 3 [https://pubmed.ncbi.nlm.nih.gov/41484215/ Prenatal Interferon-Alpha Exposure Induces Autism-Like Neurobehavioral and Neurochemical Alterations in Male Offspring]

Helminthic therapy and allergy

Jlm — Tue, 19 May 2026 18:51:25 GMT

Scientific papers not directly related

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	=== Scientific papers not directly related ===		=== Scientific papers not directly related ===

			* 2026 May 14 [https://pubmed.ncbi.nlm.nih.gov/42132472/ Gut-derived, inflammatory ILC2s disseminate type 2 immunity to remote lung in food allergen-challenged mice] (Online ahead of print)
	* 2026 [https://books.google.fr/books?hl=fr&lr=&id=Acu2EQAAQBAJ&oi=fnd&pg=PA199#v=onepage&q&f=false Microbiota in food sensitivies and allergies] (Book chapter of Microbial Approaches to Personalized Nutrition)		* 2026 [https://books.google.fr/books?hl=fr&lr=&id=Acu2EQAAQBAJ&oi=fnd&pg=PA199#v=onepage&q&f=false Microbiota in food sensitivies and allergies] (Book chapter of Microbial Approaches to Personalized Nutrition)
	* 2025 Oct 30 [https://www.researchsquare.com/article/rs-7981632/v1 Farms, Findings, and False Causation: A Systematic Review of Allergy Prevalence] (Preprint)		* 2025 Oct 30 [https://www.researchsquare.com/article/rs-7981632/v1 Farms, Findings, and False Causation: A Systematic Review of Allergy Prevalence] (Preprint)

Mechanisms underlying helminth colonization

Jlm — Tue, 19 May 2026 18:50:52 GMT

Group 2 innate lymphoid cells (ILC2s)

← Older revision		Revision as of 18:50, 19 May 2026
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	'''See also''' (maybe not directly related)		'''See also''' (maybe not directly related)

			* 2026 May 14 [https://pubmed.ncbi.nlm.nih.gov/42132472/ Gut-derived, inflammatory ILC2s disseminate type 2 immunity to remote lung in food allergen-challenged mice] (Online ahead of print)
	* 2026 Apr 28 [https://pubmed.ncbi.nlm.nih.gov/42061467/ Group 2 innate lymphoid cells: Where are we 15 years out?]		* 2026 Apr 28 [https://pubmed.ncbi.nlm.nih.gov/42061467/ Group 2 innate lymphoid cells: Where are we 15 years out?]
	* 2026 Apr 14 [https://pubmed.ncbi.nlm.nih.gov/41985445/ Training, memory, and tissue adaptation of NK cells and innate lymphoid cells]		* 2026 Apr 14 [https://pubmed.ncbi.nlm.nih.gov/41985445/ Training, memory, and tissue adaptation of NK cells and innate lymphoid cells]

Medical conditions and their response to helminthic therapy

Jlm — Tue, 19 May 2026 16:41:18 GMT

Medical conditions

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	* Pancreatic cancer: [[Helminthic therapy and cancer#Pancreatic cancer \| CTOS]]		* Pancreatic cancer: [[Helminthic therapy and cancer#Pancreatic cancer \| CTOS]]
	* Pancreatitis: [[Mechanisms underlying helminth colonization#Neprilysin alias Neutral endopeptidase (NEP) (Substance P protease) \| PTE]]		* Pancreatitis: [[Mechanisms underlying helminth colonization#Neprilysin alias Neutral endopeptidase (NEP) (Substance P protease) \| PTE]]
	* PANDAS / PANS: [[Helminthic therapy ~~personal stories~~#PANDAS / PANS \| PS]]		* Paediatric Acute-onset Neuropsychiatric Syndrome (PANS): [[Helminthic therapy and neuropsychiatric disorders#PANDAS / PANS \| PS]]
			* Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) : [[Helminthic therapy and neuropsychiatric disorders#PANDAS / PANS \| PS]]
	* Papillomavirus: [[Helminthic therapy and infectious diseases#Helminths and papillomavirus) \| SE]]		* Papillomavirus: [[Helminthic therapy and infectious diseases#Helminths and papillomavirus) \| SE]]
	* Parkinson's disease: [[Helminthic therapy personal stories#Parkinson’s disease \| PS]]		* Parkinson's disease: [[Helminthic therapy personal stories#Parkinson’s disease \| PS]]

Helminthic therapy and neuropsychiatric disorders

Jlm — Tue, 19 May 2026 16:38:36 GMT

Autism

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	See [[Helminthic therapy and autism \| '''Helminthic therapy and autism''']]		See [[Helminthic therapy and autism \| '''Helminthic therapy and autism''']]

			== PANDAS / PANS ==

			(Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections / Paediatric Acute-onset Neuropsychiatric Syndrome)

			personal stories

			* "We are almost six months past his initial inoculation (with NA). His PANDAS is pretty much completely gone, his sensory issues are back to what they were pre-PANDAS. He is dramatically improved. This is all way beyond our wildest dreams, since we had no idea these results could happen and were trying to address his allergic rhinitis and chronic ear infections with the treatment." (Reported in a private discussion, Apr 2012)

			* "I can't believe it's been almost a year since we got inoculated with hookworm… It's amazing to see my son run up to school from the end of the block on his own when at the beginning of the school year, he was almost paralyzed by panic attacks from PANDAS, a disease for which there is basically no treatment or cure aside from antibiotic administration until adulthood." (Reported in a private discussion, Jun 2012)

			* "Our son, who is 10 and has Autism as well as PANDAS, was our first child to go on TSO and he has benefited greatly from it. It is also helping quite a lot with his allergies. (High Histamines = raging BAD mood for him.) His bloodwork results have been coming back close to normal where they'd not ever been close to normal in the past. Similar with our daughter, who is almost 13 and who began TSO in January 2013. She has had PANDAS and OCD for 9-10 years, since she was a toddler, but with the addition of TSO to her regimen, she lost her OCD overnight in January and it's not returned, though she says she can feel a little "buzzing" when it's time for more TSO, and that means the benefit is starting to wane. She was doing well enough in April to take a break from IVIG, at which point her bloodwork began coming in normal. She continues TSO every 2 weeks and is now happy and stable." (Link expired)

			* “5 months without a PANDAS flare up!! Thank you helminths!! My ASD & PANDAS daughter was having horrible anxiety, involuntary movements, some really scary tongue and breathing tics and, before she got her 45 Necator Americanus helminths, she was having flares every month. I was so desperate to stop the suffering and I only regret not doing it two years ago when I first heard of helminthic therapy and thought it was just crazy. There was a dramatic worsening of tics the first few weeks. At times it seemed like she was for sure starting a new flare but the symptoms would only last for minutes or a couple hours, and there has been a complete resolution of PANDAS flare ups now. I had tried TSO before the NA and I was amazed at the immediate improvements but I just couldn't afford to pay $400 a month for the TSO. The majority of research that I found on helminths for autoimmune conditions is for NA, and the cost is better since they live 3+ years.” (Edited from several posts in this thread: [https://www.facebook.com/groups/htsupport/permalink/1068326963223258/])<!-- LVP -->

			* These two posts are about the same child:
			**“My son was very very sick when we started HDC worms. We have been on them every two weeks for over a year... Worms have changed my kids life drastically. He was on 3 antibiotics to treat his PANDAS before. He was always up and down and under weight. He gained over 5 inches in 7 months on the worms. Is 30 percentile in weight and 20 percentile now in height. This is a kid that never even made the charts.” [https://www.facebook.com/groups/htsupport/permalink/1181463555242931/]
			**“We do HDC for over a year for my PANDAS autism kid. Best thing we have ever done. He was on 3 antibiotics and still having flares before we started. He is 12 and for the first time since 4 off all antibiotics and no flares for this entire year. Ocds, tics and anxiety so much better. Using more language. Trying so many new things. Went from dangerously underweight to 30 percentile. Grew over 6 inches in one year. Overall healthier. Best thing we could have ever done. He is just so easy going and that is not what anyone would have said about him before.” [https://www.facebook.com/groups/htsupport/permalink/1187124991343454/]

			* "Good news re: my PANS / PANDAS child (age 9) - his obsessive-compulsive disorder (OCD) decreased by 95% practically overnight, following his 4th dose of 2,500 TSO. It has lasted for 2 days now, where he no longer cares where things are placed/ordered around our home. Previously, if one thing was "out of place" he would grow very agitated and angry until it was back the way he needed it to be. We started him on a half dose (1,200) of TSO at the beginning of October with 2,500 TSO every two weeks after. He would temporarily get worse after each dose, but it was worth it. His appetite has also improved lately. Best thing I have heard all year - 'Mama, I'm so happy I don't care where things go any more.” [https://www.facebook.com/groups/htsupport/permalink/1494227933966490/] And an update, two years later... “He’s still doing well. The severe OCD, constant crankiness and rages never returned. He does backslide a bit during pollen season where we live - a touch of OCD, some anger and crying over little things. As soon as he's done crying, he's himself. This happens a few times a week during pollen season. So still way, way better than he was before helminths.” [https://www.facebook.com/groups/htsupport/permalink/1469185616470722/?comment_id=2384367651619176&reply_comment_id=2385235008199107]

			* “My son’s PANDAS was essentially cured in six weeks after inoculation with NA. [https://www.facebook.com/groups/htsupport/permalink/1469185616470722/?comment_id=2389019767820631] He was five years old. He had intense separation anxiety, palilalia, verbal tics, obsessive destructive tendencies taking things apart, chewing holes in his clothing multiple times per day, not eating, attacks of enuresis of wetting his pants uncontrollably, not being able to sleep. He couldn’t go alone into any room in our house. We had to have all the lights on 24 hours per day. He would ask me, “Mama, where are you?” hundreds of times a day when I had not moved. He could only sleep lying on top of my body. This was on amoxicillin for five straight months. Off of it, he was worse. [https://www.facebook.com/groups/htsupport/permalink/1469185616470722/?comment_id=2389019767820631&reply_comment_id=2389075397815068] My son still gets a spike in anxiety when exposed to strep but he is essentially cured. He was treated eight years ago. We reinoculated multiple times but he has not had an inoculation in four years." [https://www.facebook.com/groups/htsupport/permalink/1469185616470722/?comment_id=2389019767820631&reply_comment_id=2389396524449622]

			* “We just started my 8yo pans daughter on HDC and within days she was so much better than she's been in months!” [https://www.facebook.com/groups/htsupport/permalink/1068326963223258/?comment_id=1270599359662683&comment_tracking=%7B%22tn%22%3A%22R%22%7D]

			* “Omg, my PANDAS son is infected with strep and he's NOT in a full on flare! This is HUGE. In the past when he's been infected, I know it before the doctors do. His behaviors go off the charts, and we start thinking things like maybe he needs to go to a mental institution for treatment. This time, his behaviors have increased slightly, and I was honestly thinking that maybe the HDC wasn't effective for him and this was a sign of that. Instead, he's been fighting the infection and only slightly worsened. I am hopeful for the first time in a long time!” [https://www.facebook.com/groups/htsupport/permalink/2641427349246537/] (Also see this [https://www.facebook.com/groups/htsupport/permalink/2445510625504878/ support group thread] about the same boy.)

			* “Our son is Fully recovered! the treatment actually put his Pans into remission. He has not done Flovent since last January 2019.” (Reported in October 2020.) [https://www.facebook.com/groups/htsupport/permalink/2703388759717062/?comment_id=3287677181288214]

			* “My son, who is 15, is on the autism spectrum, is gay, overweight, fatigued, depressed, and has PANDAS/POTS and OCD, along with mast cell and allergy issues. The list is long! He started using helminths to treat the PANDAS. The first dose was 5 NA in November 2019, then a second dose of 5 in May 2020. He has always struggled with being awkward and different, and had difficulty expressing what he was feeling, but I didn’t realise just how severely depressed he had become. When he told me how much he had hated himself for so long, it broke my heart. His anxiety was off the charts. He said he was suicidal. Fortunately, a month on helminths has cleared his brain. He wakes up early now, and has lost 15 lbs. It’s like night and day, like a switch turned off and his inflammation is gone, and I am so thankful for this. I wish I had given NA to him 5 years ago. He's doing so great on them. Helminths have literally saved his life.” [https://www.facebook.com/groups/htsupport/permalink/3419265288129402/]

			* “HDC (I take 10 every three weeks) have a positive impact on my mood. My case may be different from others, but... PANS is what leads to my low mood. In PANS, autoantibodies attach to dopamine and glutamate receptors in the basal ganglia, which blocks their transmission in normal amounts. I think my good mood when I take HDC is likely because it helps whatever is leading to those autoantibodies being in the wrong place (my basal ganglia receptors), so more dopamine and glutamate can reach their proper destination. Not sure if these mechanics apply to many other disorders, though.” [https://www.facebook.com/groups/htsupport/permalink/2296657347056874/?comment_id=2334347929954482&comment_tracking=%7B%22tn%22%3A%22R%22%7D]<!-- KM --> (There's more about this individual on her blog, [https://web.archive.org/web/20230513003041/https://mysymbiontjourney.wordpress.com/ Old Friends].)

	== Schizophrenia ==		== Schizophrenia ==

Helminthic therapy and autoimmune diseases

Jlm — Tue, 19 May 2026 16:38:17 GMT

Pemphigus

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	* 2025 Apr 10 [https://pubmed.ncbi.nlm.nih.gov/40332086/ Microglia/Macrophages in Autoimmune Demyelinating Encephalomyelitis (Multiple Sclerosis/Neuromyelitis Optica)]		* 2025 Apr 10 [https://pubmed.ncbi.nlm.nih.gov/40332086/ Microglia/Macrophages in Autoimmune Demyelinating Encephalomyelitis (Multiple Sclerosis/Neuromyelitis Optica)]

			== PANDAS ==

			Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections

			See [[Helminthic therapy and neuropsychiatric disorders#PANDAS / PANS \| '''Helminthic therapy and neuropsychiatric disorders#PANDAS / PANS''']]

	== Pemphigus ==		== Pemphigus ==

Helminthic therapy personal stories

Jlm — Tue, 19 May 2026 16:37:00 GMT

PANDAS / PANS

@@ Line 1,082: / Line 1,082: @@
 === PANDAS / PANS ===
-* "We are almost six months past his initial inoculation (with NA). His PANDAS is pretty much completely gone, his sensory issues are back to what they were pre-PANDAS. He is dramatically improved. This is all way beyond our wildest dreams, since we had no idea these results could happen and were trying to address his allergic rhinitis and chronic ear infections with the treatment." (Reported in a private discussion, Apr 2012)
+See [[Helminthic therapy and neuropsychiatric disorders#PANDAS / PANS | '''Helminthic therapy and neuropsychiatric disorders#PANDAS / PANS''']]
 === Parkinson’s disease ===

Human helminth care manual

John — Mon, 18 May 2026 21:00:01 GMT

❌ Antibiotics that may significantly reduce hookworm benefits

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	==== ❌ Antibiotics that may significantly reduce hookworm benefits ====		==== ❌ Antibiotics that may significantly reduce hookworm benefits ====
	<blockquote>		<blockquote>
	* <span id="Cefazolin"></span>[https://en.wikipedia.org/wiki/Cefazolin Cefazolin] (Also known as cefazoline and cephazolin.) Someone who was given a 1 gram shot of cefazolin ~~post-operatively~~ estimates that she suffered a 60% loss of effect from her hookworms for several weeks. She began to feel better after a 3-day course of prednisone taken one month after the cefazolin exposure, and was mostly back to normal at 6 weeks. However, when [https://en.wikipedia.org/wiki/Cefalexin cefalexin] (aka cephalexin), a drug related to cefazolin within the cephalosporin class, was taken by a different hookworm host for 2 days, this appeared to have no effect on his NA colony.		* <span id="Cefazolin"></span>[https://en.wikipedia.org/wiki/Cefazolin Cefazolin] (Also known as cefazoline and cephazolin.) This drug is commonly administered to patients undergoing surgery, typically as a single shot of 2 grams intravenously, adjusted for weight, within 60 minutes before the surgery commences. Someone who was given a 1 gram shot of cefazolin in this situation estimates that she suffered a 60% loss of effect from her hookworms for several weeks. She began to feel better after a 3-day course of prednisone taken one month after the cefazolin exposure, and was mostly back to normal at 6 weeks. However, when [https://en.wikipedia.org/wiki/Cefalexin cefalexin] (aka cephalexin), a drug related to cefazolin within the cephalosporin class, was taken by a different hookworm host for 2 days, this appeared to have no effect on his NA colony.
	* [https://en.wikipedia.org/wiki/Levaquin Levofloxacin] has been reported by one NA host as having "completely devastated" her colony. An egg count revealed only 14 ova, and she went from near total remission to a severe flare. "Back to ground zero." [https://www.facebook.com/groups/htsupport/permalink/1626974844025131/?comment_id=1627023594020256&comment_tracking=%7B%22tn%22%3A%22R2%22%7D]		* [https://en.wikipedia.org/wiki/Levaquin Levofloxacin] has been reported by one NA host as having "completely devastated" her colony. An egg count revealed only 14 ova, and she went from near total remission to a severe flare. "Back to ground zero." [https://www.facebook.com/groups/htsupport/permalink/1626974844025131/?comment_id=1627023594020256&comment_tracking=%7B%22tn%22%3A%22R2%22%7D]
	</blockquote>		</blockquote>

Mechanisms underlying helminth colonization

Jlm — Mon, 18 May 2026 19:45:16 GMT

Percutaneous penetration

← Older revision		Revision as of 19:45, 18 May 2026
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	== Percutaneous penetration ==		== Percutaneous penetration ==

			* 2026 May 15 [https://pubmed.ncbi.nlm.nih.gov/42139813/ Sensory behaviors of parasitic nematodes] (Online ahead of print)
	* 2025 Dec 17 [https://pubmed.ncbi.nlm.nih.gov/41479896/ Getting into host's skin: initial immune response to Schistosoma mansoni infection]		* 2025 Dec 17 [https://pubmed.ncbi.nlm.nih.gov/41479896/ Getting into host's skin: initial immune response to Schistosoma mansoni infection]
	* 2025 Sep 8 [https://helminthconference.org/wp-content/uploads/2025/10/Hydra-Helminth-Conference-Full-Programme-2025.pdf Unraveling the host-parasite interaction: regulation of the immune response in a tissue-specific manner during N. brasiliensis infection] (Conference)		* 2025 Sep 8 [https://helminthconference.org/wp-content/uploads/2025/10/Hydra-Helminth-Conference-Full-Programme-2025.pdf Unraveling the host-parasite interaction: regulation of the immune response in a tissue-specific manner during N. brasiliensis infection] (Conference)

Helminthic therapy research

Jlm — Mon, 18 May 2026 19:42:50 GMT

2026

← Older revision		Revision as of 19:42, 18 May 2026
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	* 2026 May 7 [https://www.preprints.org/manuscript/202605.0276 Autoimmune Diseases in the Interpretation of Evolutionary Medicine] (Preprint)		* 2026 May 7 [https://www.preprints.org/manuscript/202605.0276 Autoimmune Diseases in the Interpretation of Evolutionary Medicine] (Preprint)
	* 2026 May 6 [https://pubmed.ncbi.nlm.nih.gov/42097143/ Maternal helminths rewire the microbiota to promote offspring antiviral immunity] (also see conference 2026 Feb 17 [https://resvinet.org/wp-content/uploads/2026/02/RSVVW26-Abstract-Booklet.pdf Maternal Helminths Rewire the Microbiota to Promote Offspring Antiviral Immunity via Indole-3-Propionic Acid], Medscape 2026 Mar 23 [https://www.medscape.com/viewarticle/parasitic-worms-provide-insights-rsv-prevention-2026a10008ob?form=fpf Parasitic Worms Provide Insights on RSV Prevention], Conference 2025 Nov [https://academic.oup.com/jimmunol/article/214/Supplement_1/vkaf283.1609/8329627 Maternal helminth infection promotes offspring long-term antiviral immunity via microbiota], Interview 2025 Sep 29 [https://www.pew.org/en/research-and-analysis/articles/2025/09/29/a-small-worm-offers-big-clues-about-the-human-immune-system A Small Worm Offers Big Clues About the Human Immune System])		* 2026 May 6 [https://pubmed.ncbi.nlm.nih.gov/42097143/ Maternal helminths rewire the microbiota to promote offspring antiviral immunity] (also see conference 2026 Feb 17 [https://resvinet.org/wp-content/uploads/2026/02/RSVVW26-Abstract-Booklet.pdf Maternal Helminths Rewire the Microbiota to Promote Offspring Antiviral Immunity via Indole-3-Propionic Acid], Medscape 2026 Mar 23 [https://www.medscape.com/viewarticle/parasitic-worms-provide-insights-rsv-prevention-2026a10008ob?form=fpf Parasitic Worms Provide Insights on RSV Prevention], Conference 2025 Nov [https://academic.oup.com/jimmunol/article/214/Supplement_1/vkaf283.1609/8329627 Maternal helminth infection promotes offspring long-term antiviral immunity via microbiota], Interview 2025 Sep 29 [https://www.pew.org/en/research-and-analysis/articles/2025/09/29/a-small-worm-offers-big-clues-about-the-human-immune-system A Small Worm Offers Big Clues About the Human Immune System])
			* 2026 May [https://pubmed.ncbi.nlm.nih.gov/42138692/ Infection-Driven Autoimmune Amplification Versus Molecule-Specific Immune Modulation: The Dual Role of Toxocara canis in Autoimmunity]
	* 2026 Apr 30 [https://pubmed.ncbi.nlm.nih.gov/42062458/ Microbiome responses to anthelmintic treatment depend on pre-treatment helminth infection status in young Ethiopian children] -- [https://www.nature.com/articles/s43856-026-01625-3 Full text]		* 2026 Apr 30 [https://pubmed.ncbi.nlm.nih.gov/42062458/ Microbiome responses to anthelmintic treatment depend on pre-treatment helminth infection status in young Ethiopian children] -- [https://www.nature.com/articles/s43856-026-01625-3 Full text]
	* 2026 Apr 30 [https://pubmed.ncbi.nlm.nih.gov/41984489/ Helminth Excretory/Secretory Proteins Ameliorate Colitis Through Preservation of Intestinal Homeostasis]		* 2026 Apr 30 [https://pubmed.ncbi.nlm.nih.gov/41984489/ Helminth Excretory/Secretory Proteins Ameliorate Colitis Through Preservation of Intestinal Homeostasis]

Helminthic therapy and vaccines

Jlm — Mon, 18 May 2026 19:40:59 GMT

Scientific publications

← Older revision		Revision as of 19:40, 18 May 2026
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	== Scientific publications ==		== Scientific publications ==

			* 2026 May 11 [https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2026.1827532/abstract Helminth infection modulates the immunogenicity of COVID-19 vaccines in mice without compromising protective efficacy] (Not yet published)
	* 2026 Apr 27 [https://www.researchsquare.com/article/rs-9305049/v1 Helminth infection is linked to an impaired neutralisation response to SARS-CoV-2 post vaccination] (Preprint)		* 2026 Apr 27 [https://www.researchsquare.com/article/rs-9305049/v1 Helminth infection is linked to an impaired neutralisation response to SARS-CoV-2 post vaccination] (Preprint)
	* 2026 Apr 6 [https://pubmed.ncbi.nlm.nih.gov/41942307/ The forgotten variable in vaccine immunology: helminth infection]		* 2026 Apr 6 [https://pubmed.ncbi.nlm.nih.gov/41942307/ The forgotten variable in vaccine immunology: helminth infection]

Helminthic therapy research

Jlm — Mon, 18 May 2026 19:37:15 GMT

2026

← Older revision		Revision as of 19:37, 18 May 2026
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	===2026===		===2026===

			* 2026 May 15 [https://pubmed.ncbi.nlm.nih.gov/42142639/ Ecological and Biomedical Functions of Parasitofauna: Mechanistic and Evolutionary Perspectives]
	* 2026 May 7 [https://www.preprints.org/manuscript/202605.0276 Autoimmune Diseases in the Interpretation of Evolutionary Medicine] (Preprint)		* 2026 May 7 [https://www.preprints.org/manuscript/202605.0276 Autoimmune Diseases in the Interpretation of Evolutionary Medicine] (Preprint)
	* 2026 May 6 [https://pubmed.ncbi.nlm.nih.gov/42097143/ Maternal helminths rewire the microbiota to promote offspring antiviral immunity] (also see conference 2026 Feb 17 [https://resvinet.org/wp-content/uploads/2026/02/RSVVW26-Abstract-Booklet.pdf Maternal Helminths Rewire the Microbiota to Promote Offspring Antiviral Immunity via Indole-3-Propionic Acid], Medscape 2026 Mar 23 [https://www.medscape.com/viewarticle/parasitic-worms-provide-insights-rsv-prevention-2026a10008ob?form=fpf Parasitic Worms Provide Insights on RSV Prevention], Conference 2025 Nov [https://academic.oup.com/jimmunol/article/214/Supplement_1/vkaf283.1609/8329627 Maternal helminth infection promotes offspring long-term antiviral immunity via microbiota], Interview 2025 Sep 29 [https://www.pew.org/en/research-and-analysis/articles/2025/09/29/a-small-worm-offers-big-clues-about-the-human-immune-system A Small Worm Offers Big Clues About the Human Immune System])		* 2026 May 6 [https://pubmed.ncbi.nlm.nih.gov/42097143/ Maternal helminths rewire the microbiota to promote offspring antiviral immunity] (also see conference 2026 Feb 17 [https://resvinet.org/wp-content/uploads/2026/02/RSVVW26-Abstract-Booklet.pdf Maternal Helminths Rewire the Microbiota to Promote Offspring Antiviral Immunity via Indole-3-Propionic Acid], Medscape 2026 Mar 23 [https://www.medscape.com/viewarticle/parasitic-worms-provide-insights-rsv-prevention-2026a10008ob?form=fpf Parasitic Worms Provide Insights on RSV Prevention], Conference 2025 Nov [https://academic.oup.com/jimmunol/article/214/Supplement_1/vkaf283.1609/8329627 Maternal helminth infection promotes offspring long-term antiviral immunity via microbiota], Interview 2025 Sep 29 [https://www.pew.org/en/research-and-analysis/articles/2025/09/29/a-small-worm-offers-big-clues-about-the-human-immune-system A Small Worm Offers Big Clues About the Human Immune System])

Mechanisms underlying helminth colonization

Jlm — Sun, 17 May 2026 20:08:12 GMT

CD8+ virtual memory T cells

← Older revision		Revision as of 16:41, 19 May 2026
(2 intermediate revisions by the same user not shown)
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	* Pancreatic cancer: [[Helminthic therapy and cancer#Pancreatic cancer \| CTOS]]		* Pancreatic cancer: [[Helminthic therapy and cancer#Pancreatic cancer \| CTOS]]
	* Pancreatitis: [[Mechanisms underlying helminth colonization#Neprilysin alias Neutral endopeptidase (NEP) (Substance P protease) \| PTE]]		* Pancreatitis: [[Mechanisms underlying helminth colonization#Neprilysin alias Neutral endopeptidase (NEP) (Substance P protease) \| PTE]]
	* PANDAS / PANS: [[Helminthic therapy ~~personal stories~~#PANDAS / PANS \| PS]]		* Paediatric Acute-onset Neuropsychiatric Syndrome (PANS): [[Helminthic therapy and neuropsychiatric disorders#PANDAS / PANS \| PS]]
			* Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) : [[Helminthic therapy and neuropsychiatric disorders#PANDAS / PANS \| PS]]
	* Papillomavirus: [[Helminthic therapy and infectious diseases#Helminths and papillomavirus) \| SE]]		* Papillomavirus: [[Helminthic therapy and infectious diseases#Helminths and papillomavirus) \| SE]]
	* Parkinson's disease: [[Helminthic therapy personal stories#Parkinson’s disease \| PS]]		* Parkinson's disease: [[Helminthic therapy personal stories#Parkinson’s disease \| PS]]

← Older revision		Revision as of 20:08, 17 May 2026
(5 intermediate revisions by the same user not shown)
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	* 2025 Feb 7 [https://www.science.org/doi/10.1126/sciimmunol.adk4841?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed IL-4 induces CD22 expression to restrain the effector program of virtual memory T cells] (Also reported by ScienceDaily [https://www.sciencedaily.com/releases/2025/02/250207152719.htm])		* 2025 Feb 7 [https://www.science.org/doi/10.1126/sciimmunol.adk4841?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed IL-4 induces CD22 expression to restrain the effector program of virtual memory T cells] (Also reported by ScienceDaily [https://www.sciencedaily.com/releases/2025/02/250207152719.htm])
	* 2023 May [https://escholarship.mcgill.ca/concern/theses/s7526j95z?locale=en Coordinated Parasitic and Microbial Mechanisms Regulate Effector CD8+ T cell Heterogeneity during Helminth Infection] (Thesis, McGill)		* 2023 May [https://escholarship.mcgill.ca/concern/theses/s7526j95z?locale=en Coordinated Parasitic and Microbial Mechanisms Regulate Effector CD8+ T cell Heterogeneity during Helminth Infection] (Thesis, McGill)
			* 2023 Feb 1 [https://pubmed.ncbi.nlm.nih.gov/36524995/ Helminth Infection-Induced Increase in Virtual Memory CD8 T Cells Is Transient, Driven by IL-15, and Absent in Aged Mice]
			* 2018 Oct 30 [https://pubmed.ncbi.nlm.nih.gov/30375396/ Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection]
	* 2018 Oct 25 [https://pubmed.ncbi.nlm.nih.gov/30361537 Virtual memory CD8 T cells expanded by helminth infection confer broad protection against bacterial infection]		* 2018 Oct 25 [https://pubmed.ncbi.nlm.nih.gov/30361537 Virtual memory CD8 T cells expanded by helminth infection confer broad protection against bacterial infection]

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	* 2019 Feb [https://pubmed.ncbi.nlm.nih.gov/30500088/ IL-4Rα-expressing CD11c+ cells contribute to driving optimal cellular responses during Schistosoma mansoni infection in mice]		* 2019 Feb [https://pubmed.ncbi.nlm.nih.gov/30500088/ IL-4Rα-expressing CD11c+ cells contribute to driving optimal cellular responses during Schistosoma mansoni infection in mice]
	* 2018 Oct 31 [https://pubmed.ncbi.nlm.nih.gov/30379806 The Foxp3+ regulatory T-cell population requires IL-4Rα signaling to control inflammation during helminth infections]		* 2018 Oct 31 [https://pubmed.ncbi.nlm.nih.gov/30379806 The Foxp3+ regulatory T-cell population requires IL-4Rα signaling to control inflammation during helminth infections]
	* 2018 Oct 30 [https://pubmed.ncbi.nlm.nih.gov/30375396/ Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection~~] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC6207712/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC6207712/pdf/41467_2018_Article_6978.pdf PDF~~]		* 2018 Oct 30 [https://pubmed.ncbi.nlm.nih.gov/30375396/ Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection]
	* 2018 Sep 21 [https://pubmed.ncbi.nlm.nih.gov/30238872/ Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion]		* 2018 Sep 21 [https://pubmed.ncbi.nlm.nih.gov/30238872/ Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion]
	* 2018 Sep 2 [https://helminthconference.org/wp-content/uploads/2023/05/2018-Hydra-Conference-Booklet.pdf Partial removal of IL-4 receptor alpha within the FoxP3+ regulatory T cell population impairs the control of inflammation in disease] (Conference)		* 2018 Sep 2 [https://helminthconference.org/wp-content/uploads/2023/05/2018-Hydra-Conference-Booklet.pdf Partial removal of IL-4 receptor alpha within the FoxP3+ regulatory T cell population impairs the control of inflammation in disease] (Conference)
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	=== Serine proteases ===		=== Serine proteases ===

			* 2024 Mar 8 [https://dspace.cuni.cz/handle/20.500.11956/188729 Characterization of serine proteases of Schistosoma mansoni involved in interaction with host] (Thesis, Prague)

	* 2023 Feb [https://pubmed.ncbi.nlm.nih.gov/36681328/ In silico analysis of two Haemonchus spp. serine protease peptides (S28) and their immunomodulatory activity in vitro]		* 2023 Feb [https://pubmed.ncbi.nlm.nih.gov/36681328/ In silico analysis of two Haemonchus spp. serine protease peptides (S28) and their immunomodulatory activity in vitro]
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	* 2026 Feb [https://pubmed.ncbi.nlm.nih.gov/41707071/ The Evolution and Ecology of Host Manipulation in Helminth Parasites: A Phylogenetic Meta-Analysis]		* 2026 Feb [https://pubmed.ncbi.nlm.nih.gov/41707071/ The Evolution and Ecology of Host Manipulation in Helminth Parasites: A Phylogenetic Meta-Analysis]
	* 2026 Feb [https://pubmed.ncbi.nlm.nih.gov/41577022/ Fasciola hepatica excretory and secretory products reprogram the Kupffer cell transcriptome to modulate hepatic damage progression]		* 2026 Feb [https://pubmed.ncbi.nlm.nih.gov/41577022/ Fasciola hepatica excretory and secretory products reprogram the Kupffer cell transcriptome to modulate hepatic damage progression]
	2026 Jan 2 [https://pubmed.ncbi.nlm.nih.gov/41520315/ Capturing gene-cell duality in a cat's cradle]		* 2026 Jan 2 [https://pubmed.ncbi.nlm.nih.gov/41520315/ Capturing gene-cell duality in a cat's cradle]
	* 2026 [https://biocomjournal.com/index.php/bcs/article/view/15 Parasites as drivers of host diversification, including domestication] -- [https://biocomjournal.com/index.php/bcs/article/view/15/20 Full text] \| [https://biocomjournal.com/index.php/bcs/article/view/15/19 PDF]		* 2026 [https://biocomjournal.com/index.php/bcs/article/view/15 Parasites as drivers of host diversification, including domestication] -- [https://biocomjournal.com/index.php/bcs/article/view/15/20 Full text] \| [https://biocomjournal.com/index.php/bcs/article/view/15/19 PDF]
	* 2025 Oct 24 [https://ibn.idsi.md/vizualizare_articol/239161 Relațiile inter - și intraspecifice ale paraziţilor în corpul gazdei] (Inter - and intraspecific relationships of parasites in the host body) (Conference, Romanian)		* 2025 Oct 24 [https://ibn.idsi.md/vizualizare_articol/239161 Relațiile inter - și intraspecifice ale paraziţilor în corpul gazdei] (Inter - and intraspecific relationships of parasites in the host body) (Conference, Romanian)
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	* 2025 Jun 18 [https://pubmed.ncbi.nlm.nih.gov/40606633/ TIM4+ macrophages suppress the proinflammatory response to maintain the chronic alveolar echinococcosis infection]		* 2025 Jun 18 [https://pubmed.ncbi.nlm.nih.gov/40606633/ TIM4+ macrophages suppress the proinflammatory response to maintain the chronic alveolar echinococcosis infection]
	* 2025 May [https://pubmed.ncbi.nlm.nih.gov/40369966/ RNA-Sequencing in Elucidating Immune Responses to Haemonchus contortus Infection in Small Ruminants: Systematic Review] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC12079082/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC12079082/pdf/PIM-47-e70009.pdf PDF]		* 2025 May [https://pubmed.ncbi.nlm.nih.gov/40369966/ RNA-Sequencing in Elucidating Immune Responses to Haemonchus contortus Infection in Small Ruminants: Systematic Review] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC12079082/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC12079082/pdf/PIM-47-e70009.pdf PDF]
	* 2025 [https://pubmed.ncbi.nlm.nih.gov/41062238/ Epithelial cytokines in soil-transmitted helminth infections]		* 2025 [https://pubmed.ncbi.nlm.nih.gov/41062238/ Epithelial cytokines in soil-transmitted helminth infections](Bachelor, Prague, Czech)
	* 2024 Jul 27 [https://pubmed.ncbi.nlm.nih.gov/39068442/ Modulation of the intestinal mucosal and cell-mediated response against natural helminth infection in the African catfish Clarias gariepinus] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC11282724/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC11282724/pdf/12917_2024_Article_4153.pdf PDF]		* 2024 Jul 27 [https://pubmed.ncbi.nlm.nih.gov/39068442/ Modulation of the intestinal mucosal and cell-mediated response against natural helminth infection in the African catfish Clarias gariepinus] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC11282724/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC11282724/pdf/12917_2024_Article_4153.pdf PDF]
	* 2024 Jul [https://pubmed.ncbi.nlm.nih.gov/38877178/ Genetic and environmental interactions contribute to immune variation in rewilded mice] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC11224019/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC11224019/pdf/41590_2024_Article_1862.pdf PDF]		* 2024 Jul [https://pubmed.ncbi.nlm.nih.gov/38877178/ Genetic and environmental interactions contribute to immune variation in rewilded mice] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC11224019/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC11224019/pdf/41590_2024_Article_1862.pdf PDF]
			* 2024 May 31 [https://dspace.cuni.cz/handle/20.500.11956/190013 Helminth-host interactions on hormonal level] (Bachelor, Prague, Czech)
	* 2024 May 19 [https://scholarspace.library.gwu.edu/concern/gw_etds/8s45q9551 Towards a Molecular Understanding of Host Specificity in Hookworm Infections] (Thesis)		* 2024 May 19 [https://scholarspace.library.gwu.edu/concern/gw_etds/8s45q9551 Towards a Molecular Understanding of Host Specificity in Hookworm Infections] (Thesis)
	* 2024 May 15 [https://pubmed.ncbi.nlm.nih.gov/38786064/ Single-Cell Transcriptomic Profiling Unveils Dynamic Immune Cell Responses during Haemonchus contortus Infection] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC11120485/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC11120485/pdf/cells-13-00842.pdf PDF]		* 2024 May 15 [https://pubmed.ncbi.nlm.nih.gov/38786064/ Single-Cell Transcriptomic Profiling Unveils Dynamic Immune Cell Responses during Haemonchus contortus Infection] -- [https://pmc.ncbi.nlm.nih.gov/articles/PMC11120485/ Full text] \| [https://pmc.ncbi.nlm.nih.gov/articles/PMC11120485/pdf/cells-13-00842.pdf PDF]