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::This study shows that lung remodelling from a prior helminth infection promotes recovery and less severe outcomes in mice challenged with SARS-CoV-2. | ::This study shows that lung remodelling from a prior helminth infection promotes recovery and less severe outcomes in mice challenged with SARS-CoV-2. | ||
* 2022 Jun 28 [https://pubmed.ncbi.nlm.nih.gov/35764965/ Helminth antigens differentially modulate the activation of CD4 + and CD8 + T lymphocytes of convalescent COVID-19 patients in vitro] | * 2022 Jun 28 [https://pubmed.ncbi.nlm.nih.gov/35764965/ Helminth antigens differentially modulate the activation of CD4 + and CD8 + T lymphocytes of convalescent COVID-19 patients in vitro] -- [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241220/ Full text] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241220/pdf/12916_2022_Article_2441.pdf PDF] | ||
:{{Quote|indent}}Our data offer a plausible explanation for the moderate incidence of COVID-19 in Africa and support the hypothesis that helper T cell-mediated immune responses to SARS-CoV-2 are mitigated in the presence of helminth antigens, while virus-specific cytotoxic T cell responses are maintained.{{Quote|/indent}} | :{{Quote|indent}}Our data offer a plausible explanation for the moderate incidence of COVID-19 in Africa and support the hypothesis that helper T cell-mediated immune responses to SARS-CoV-2 are mitigated in the presence of helminth antigens, while virus-specific cytotoxic T cell responses are maintained.{{Quote|/indent}} |