Helminth therapy studies in murine models

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Murine studies by disease

Obesity

• 2025 Jun 12 Intestinal lymphatic vasculature is functionally adapted to different drainage regions and is altered by helminth infection -- Full text | PDF "Collectively, these observations demonstrate that helminth infections alter the structure of duodenal lacteals and compromise duodenal lymphatic lipid uptake, leading to lipid accumulation in epithelial cells and, under high-fat diet conditions, decreased weight gain".

Counterpart murine models vs human helminths

• Necator Americanus : Nippostrongylus brasiliensis, Heligmosomoides polygyrus bakeri [1].
• Trichuris Trichura : Trichuris Muris

Methodology

• 2025 Apr 6 Cultivation of Heligmosomoides polygyrus: an immunomodulatory nematode parasite and its secreted products -- Full text | PDF

• 2021 Apr 22 Rodent Models for the Study of Soil-Transmitted Helminths: A Proteomics Approach -- Full text | PDF

An intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. Wikipedia:Helminths

An intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. Wikipedia:Helminths