Helminthic therapy and rhinosinusitis
Rhinosinusitis is a simultaneous infection of the nasal mucosa (rhinitis) and an infection of the mucosa of the paranasal sinuses (sinusitis). A distinction is made between acute rhinosinusitis and chronic rhinosinusitis.
The scientific evidence[edit | edit source]
See
- ✅ 2015 Apr 18 Overcoming Evolutionary Mismatch by Self-Treatment with Helminths: Current Practices and Experience (PDF) This was the first study to probe the methods and outcomes reported by individuals self-treating with helminths.
See also
- 2025 Apr IL-25 Enhances B Cell Responses in Type 2 Inflammation Through IL-17RB Receptor -- Full text | PDF
- 2022 Feb 7 Expression of CD8+Treg cells in chronic rhinosinusitis and its correlation with eosinophilic infiltration (Chinese)
- 2020 Jan 31 Type 2 inflammation suppression by T-regulatory cells attenuates the eosinophil recruitment in mucosa of chronic sinusitis
- 2017 Feb IFN-γ Blocks Development of an Asthma Phenotype in Rhinovirus-Infected Baby Mice by Inhibiting Type 2 Innate Lymphoid Cells -- Full text | [1]
- 2014 Aug Neonatal rhinovirus induces mucous metaplasia and airways hyperresponsiveness through IL-25 and type 2 innate lymphoid cells -- Full text | PDF
- 2013 Aug 15 IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps -- Full text | PDF
The anecdotal evidence[edit | edit source]
Rhinitis[edit | edit source]
The first report is more detailed than the quotes that follow it.
- “Anyone who doesn’t try this isn’t suffering enough!” (Comment on a now defunct forum from someone whose severe rhinitis had driven him to the point of suicide, but who had been given a new lease of life by a dose of hookworms.)
- "Now, at nearly two years since I began helminthic therapy I am nasally more normal than at any time in my life." [2]
- “I have been getting HDC for the past 6 months for allergic rhinitis and IBS, both of which which I have been battling for years. The improvements were amazing! I've been taking a dose of 25 - 30 every 3 - 4 weeks since September. Both issues are virtually gone when i'm on them. The effects seem to last for 3 - 4 weeks. I can tell when I need a new dose because my symptoms suddenly re-appear. Then when I take another dose within a day or two, huge improvement!” (Reported to a closed group, Mar 2014)
- ☹️ “I hosted (hookworms) over three years and saw no benefits mainly for allergic rhinitis and fatigue.” [4]
Sinusitis[edit | edit source]
The first two reports are more detailed than the quotes that follow them.
- "... my father (who is the big sinusitis person)... had such an issue with this that for almost 30 years he lost his taste and smell every day at some point, and often for days at a time... By about 6 months after getting hookworm, the problem resolved." (Link expired)
- "I inoculated at two months after my sinus surgery and did so because at the time I was having green discharge and mucus that was almost as bad as before the surgery. Starting only 6 days after inoculating and continuing for the 4 month until now, the signs of sinusitis with purulent nasal discharge and PND have been the best 4 month period in the approx. 15 months since the sinusitis abruptly started. And this is with NO antibiotics, which I took for months before submitting to the surgery… At this point I would continue HT even if I had no further improvement." (Reported to the Facebook Helminthic Therapy Support Group [5], Jul 2012)
- "… the worms have totally changed my body's reaction to a cold virus. In the past, I would get an immediate sinus infection (post nasal drip, sinus pain, sinuses filled with pus). This time, I have a sore throat and a slight fever. This is awesome!" (Reported in a private discussion, Sept 2012)
- (From a 22 year old male with perennial ‘non-allergic' chronic sinusitis / nasal congestion, since age ~15) “I have blown my nose once every 10-20 minutes while awake for the past 7+ years. Waking up was a process which involved going through hell. Sleep at times has been far from restful due to waking up unable to breathe (too congested)… nasal steroids, nasal mast cell stabilizers and neti pots were effective but each presents their own side effects and issues and I was unable to ever use them in dosage significant enough to achieve relief of symptoms… A significant laundry list of surgeries, dietary supplements, lifestyle changes, voodoo and bullshit was tried in order to achieve relief. I self-infected 25 hookworm (and) began to experience symptom relief (after) about 2.75-3.0 months… I began, all at once, to have a suddenly very dry throat. A lot of hacking coughing occurred and I drank a lot of water but it was, basically, just a surprisingly sudden lack of unhealthy mucus. I can literally trace symptom relief back to this exact moment. The next morning was the first morning I woke up with a more-or-less clear nose in about the last seven years. I have woken up with an increasingly clear nose every day since then and today is the first day in seven years that I woke up with absolutely nothing in my nose at all… I actually forgot to use my nasal steroids as well. I don't think I need them anymore. I am waking up rested after just 7-8 hours of sleep.” [6]
- “I’ve just hit the 14th week with 25 NA on board and my sinus inflammation has improved about 80 percent.” [7]
- “I have an ideopathic sinus condition. I endure massive sinus floods for 4-5 hours and am oh so stopped up, low energy, and miserable the rest of the time. It's about 6 months since I got my first 5 hookworms, with another 10 administered 3 months later. Instead of where I typically have been at this point after the twice-yearly respite provided by prednisone, I AM BREATHING WELL. I have had only a very few sinus floods. I am sleeping (because I am breathing well at night.) I have energy. I am so encouraged.” [8]
- "Now, at nearly two years since I began helminthic therapy I am nasally more normal than at any time in my life." [9]
- “I had chronic sinus infections for years that I managed with antibiotics, allergy meds, and irrigation. I started NA for celiac (the symptoms of which were, for me, way worse than sinusitis) and within a couple months my head was clear for the first time in years. It was amazing. My worms died about a year and a half later (I only had 10). I only realized they had died when my sinus infections returned. Four-plus months of face and head misery this winter got me in gear to get more NA.” [10]
Nasal polyps[edit | edit source]
- "My father has something called Samter's syndrome which includes nasal polyps, chronic rhinitis, and aspirin sensitivity. For 20-25 years, he had little sense of taste or smell, due to polyps on his sinus nerve, and he had multiple surgeries to remove them. Starting about 6 months after getting hookworms, the polyps went away, never to return. He's now had his sense of taste and smell all day every day, acutely, for a good 3 1⁄2 years.” Two years after posting this, the contributor added, “Now he is getting the same efficacy from HDC." (Links expired)
- "Recurring nasal polyps… I have reversed them without surgery, I can smell so well now that shampoo can give me a headache.. I can smell soap.. I can properly taste food.. and I feel generally great." (Link expired)