Helminthic therapy and autoimmune diseases

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An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms.

General reviews

See also

• 2023 Microbiome-Induced Autoimmunity and Novel Therapeutic Intervention (Book chapter of Neuroinflammation, Gut-Brain Axis and Immunity in Neuropsychiatric Disorders)

Ankylosing spondylitis

• 2025 Mar 4 Clonorchis sinensis excretory/secretory proteins ameliorate inflammation in rheumatoid arthritis and ankylosing spondylitis -- Full text | PDF

• 2024 Apr A potential role of protein extractions from Metagonimus yokogawai in amelionating inflammation in patients with ankylosing spondylitis

• 2021 Feb 25 Clonorchis sinensis-Derived Protein Attenuates Inflammation and New Bone Formation in Ankylosing Spondylitis -- Full text | PDF

Complementary or alternative treatments

See

• 2009 Induction of Tolerogenic Dendritic Cells by Vitamin D Receptor Agonists (Chapter of Dendritic Cells)

The reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat or prevent chronic inflammation, autoimmune disease and other immune-related disorders, including allergy.