Medical conditions and their response to helminthic therapy

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This page is still being developed, so please call back later to read further details as they are added.

This page aims to list the medical conditions and their response to helminthic therapy.

List by big categories

Positive effects

• Inflammatory diseases
• Autoimmune diseases
• Asthma and allergies
• Food intolerances
• Eczema
• Irritable Bowel Syndrome (IBS) / Leaky gut
• Autism
• Neurodevelopmental diseases
• Neuropsychiatric diseases
• Neurodegenerative diseases

Mixed effects

Cancer

None of the domesticated helminth species used in therapy have been reported to cause cancer, but a number of non-therapeutic helminths are well known for their involvement in this disease. See the following page for more detail.

• Cancer

Infectious diseases

Effects on preexisting infectious diseases are dependent on the species of helminth being hosted, and the dosages used. There are generally far less issues with the four domesticated species used in therapy. See this page for more detail.

• Infectious diseases

Potential negative effects

In therapeutic helminths, these are largely associated with the use of excessive doses, are typically transient and are confined to the period immediately following the initial introduction of the helminths.

List by medical specialty

• Gastroenterology: Intestinal Bowel Diseases (Crohn and Ulcerative colitis), Eosinophilic esophagitis (EE / EoE), Irritable bowel syndrome, Gastric cancer, Colitis cancer
• Rheumatology: Autoimmune diseases (Rheumatoid arthritis, Ankylosing spondylitis, Lupus, Systemic lupus erythematosus, Dermatomyositis, Giant cell arteritis), Raynaud's Disease, Ehlers-Danlos syndrome, Sjögren's syndrome, Septic arthritis, Osteoarthritis, Osteoporosis

List by medical conditions

SE = Scientific evidence, PTE = Potential therapeutic effect, PNE = Potential negative effect (unknown with helminthic therapy), PS = Personnal stories

• Absence seizures: PS
• Acne: PS
• Actinic keratosis: PS
• Addison’s disease: PS
• Adhesions: PS
• Adrenal fatigue: PS
• Aging / Ageing: SE, PS
• Alcohol intolerance: PS
• Alopecia: PS
• Alopecia areata: SE, PS
• Allergy
• Allodynia
• Alopecia
• Alzheimer's
• Anaphylaxis
• Anaemia (anemia)
• Angioedema
• Ankylosing spondylitis
• Anxiety
• Appetite
• Arrhythmia
• Arteritis
• Arthritis
• Arthritis, IBD-related non erosive
• Asthma
• Atherosclerosis
• Aspirin-induced asthma
• Attention deficit hyperactivity disorder (ADHD, ADD)
• Autism
• Autoimmune disease
• Autoimmune hepatitis
• Autoimmune kidney disease
• Autoimmune pain
• Balanitis
• Barrett's Oesophagus
• Basedow's disease
• Bipolar disorder
• Bloating
• Body temperature, poor control of
• Brain fog
• Bronchiectasis
• Bronchitis
• Bruising
• Blood pressure
• Body weight
• Bone healing ability, loss of in the elderly
• Cancer
• Candida
• Car sickness
• Cardiovascular disease
• Celiac / Coeliac disease
• Chemical sensitivity
• Chronic fatigue syndrome (EM/CFS)
• Chronic inflammatory demyelinating polyneuropathy (CIPD)
• Chronic obstructive pulmonary disease (COPD)
• Clostridium difficile (C. diff) infection
• Cognition, poor
• Cognitive dysfunction
• Colitis
• Constipation
• COVID-19
• Cracked heels
• Cramps (abdominal)
• Cranial arteritis
• Crohn’s colitis
• Crohn's disease
• Cystic fibrosis
• Dandruff
• Dementia
• Depression / low mood
• Dermatitis
• Dermatitis herpetiformis
• Dermatographia
• Dermatomyositis
• Developmental delay
• Diabetes type 1
• Diabetes type 2
• Diarrhea / diarrhoea
• Diverticular disease (diverticulosis / diverticulitis)
• Dry eye syndrome (DES)
• Dysautonomia
• Dysmenorrhoea / dysmenorrhea
• Ehlers–Danlos syndromes (EDS)
• Encephalitis
• Eczema
• Endolymphatic hydrops
• Endometriosis
• Erythromelalgia
• Eosinophilic enterocolitis
• Eosinophilic esophagitis (EE / EoE)
• Fatigue
• Fertility
• Fibromyalgia
• Food allergy
• Food intolerance
• Gastric cancer
• GERD (reflux)
• Giant cell arteritis
• Glandular fever
• Glaucoma
• Gluten-related disorders
• Graft-versus-host disease (GVHD)
• Graves' disease
• Gluten ataxia
• Gluten sensitivity
• Gut microbiota
• Hashimoto's thyroiditis
• Hair colour change: PS
• Hair growth: PS
• Hair loss: PS
• Headaches
• Heavy metal accumulation
• Helicobacter pylori infection
• Hepatitis
• Herpes zoster
• High blood pressure
• Histamine intolerance
• HIV
• Hives
• Horton's disease
• Hot flashes (hot flushes)
• Hyperactivity
• Hyperemesis gravidarum
• Hypertension
• Hyperthyroidism
• Hypochlorhydria
• Hypocortisolism
• Hypoglycemia / Hypoglycaemia
• Hypothyroidism
• Idiopathic urticaria and eczema
• IgA nephropathy
• Immune disorders
• Infectious diseases
• Inflammaging: SE, PS
• Inflammation
• Inflammatory bowel disease (IBD)
• Influenza: SE
• Insect bite reactions
• Insulin resistance
• Interstitial cystitis (IC)
• Interstitial lung disease (ILD)
• Irritability
• Irritable bowel syndrome (IBS)
• Joint replacement, failure of
• Keratoconjunctivitis sicca (KCS)
• Keratosis pilaris
• Kidney pathology
• Labyrinthitis
• Lactose intolerance
• Leaky gut syndrome
• Leg ulcers, recalcitrant
• Lichen planus
• Lichen sclerosus
• Lifespan reduction
• Liver
• Long Covid
• Low mood
• Lupus
• Lyme disease
• Lymphocytic colitis
• Macular degeneration / age-related macular degeneration (AMD): PTE
• Malaria
• Malnutrition
• Mast cell disorders (MCAS, MCAD)
• Microscopic colitis
• Memory loss
• Ménière's disease
• Menstruation, irregular
• Menstruation, painful
• Menstruation
• Metabolic syndrome
• Migraine
• Miscarriage
• Mixed connective tissue disease (MCTD)
• Mood
• Mold (mould) illness / sensitivity
• Mononucleosis / infectious mononucleosis / glandular fever
• Mouth ulcers
• Multiple chemical sensitivity (MCS)
• Multiple sclerosis (MS)
• Muscle mass loss in the elderly
• Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
• Myasthenia gravis
• Myodesopsia (floaters)
• Myopia
• Narcolepsy
• Nasal congestion
• Nasal polyps
• Neurodegenerative diseases
• Neuropsychiatric disorders
• Night terror
• Non-alcoholic fatty liver disease (NAFLD)
• Non-coeliac / celiac gluten sensitivity (NCGS)
• Nutritional deficiencies
• Obesity
• Obsessive-compulsive disorder (OCD)
• Obstructive sleep apnea
• Oral health
• Organ transplantation
• Osteoarthritis
• Osteoporosis
• Pain, chronic
• Palpitations
• Pancolitis
• PANDAS / PANS
• Parkinson's disease
• Periodontitis (gum disease)
• Pertussis: ❓ PNE
• Peripheral neuropathy
• Polymyalgia rheumatica (PMR)
• Postural orthostatic tachycardia syndrome (POTS)
• Preeclampsia
• Premature birth
• Premenstrual Syndrome (PMS)
• Primary adrenal insufficiency
• Primary sclerosing cholangitis (PSC)
• Prostatitis
• Psoriasis
• Psoriatic arthritis (PsA)
• Psychosis
• Raynaud syndrome / Raynaud's phenomenon
• Rhinitis
• Respiratory syncytial virus (RSV) infection
• Restless legs syndrome (RLS)
• Rheumatoid arthritis (RA)
• Rhinitis
• Rosacea
• Salicylate intolerance
• Samter's triad / Samter's syndrome
• Sacroiliitis
• Sarcoidosis
• Sciatica
• Scleroderma
• Scleroderma
• Schizophrenia
• Seborrhoeic dermatitis / seborrheic dermatitis
• Sensory hypersensitivity
• Sepsis
• Sexual function
• Shingles
• Sinusitis
• Sjogren's syndrome
• Sleep
• Sleep apnea
• Sleep, problems with
• Sleep terror
• Small intestinal bacterial overgrowth (SIBO)
• Stomach acid
• Stress
• Suicide
• Sweet syndrome (SS)
• Systemic lupus erythematosus (SLE)
• Temporal arteritis
• Tendinopathy (tendinitis / tendonitis)
• Testicular atrophy
• Thyroid disease
• Tinnitus
• Tourette Syndrome
• Travel sickness
• Trimethylaminuria (TMAU)
• Tuberculosis
• Ulcer, leg
• Ulcerative colitis
• Ulcerative proctitis
• Undifferentiated connective tissue disease (UCTD)
• Urinary tract infections (UTIs)
• Urticaria
• Vaccines
• Venous thromboembolism (VTE)
• Vertigo
• Vitiligo
• Warts
• Weight, excess
• Weight, insufficient
• Whooping cough: ❓ PNE

The reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat or prevent chronic inflammation, autoimmune disease and other immune-related disorders, including allergy.

Irritable bowel syndrome is a widespread condition involving recurrent abdominal pain and diarrhoea or constipation. Wikipedia:Irritable Bowel Syndrome

An intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. Wikipedia:Helminths

An intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. Wikipedia:Helminths

Ulcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD) which specifically affects the large intestine, or colon, causing characteristic ulcers, or open sores. The main symptom of active disease is constant diarrhea mixed with blood, of gradual onset.

Eosinophilic esophagitis is an allergic inflammatory condition of the esophagus. Symptoms are difficulty swallowing, food impaction and heartburn. The disease was first described in children but also occurs in adults. It is not well understood, but food allergy may play a significant role.

Eosinophilic esophagitis is an allergic inflammatory condition of the esophagus. Symptoms are difficulty swallowing, food impaction and heartburn. The disease was first described in children but also occurs in adults. It is not well understood, but food allergy may play a significant role.

a change which is a result or consequence of an action or other cause.

Inflammatory bowel disease is a group of conditions affecting the gastrointestinal (GI) tract, particularly the colon and small intestine. The major types of IBD are Crohn's disease and ulcerative colitis (UC).

Also known as regional enteritis, this is an inflammatory disease of the intestines that may affect any part of the gastrointestinal tract from mouth to anus, causing a wide variety of symptoms. It primarily causes abdominal pain, diarrhea (which may be bloody if inflammation is severe), vomiting or weight loss, but may also cause complications outside the gastrointestinal tract such as skin rashes, arthritis, inflammation of the eye, tiredness and lack of concentration.

The specific population of microorganisms living in a certain part of the body, such as the gut. "Microbiome" refers to all the microorganisms living in and on the body, or the genome of these microorganisms. These two terms are often used interchangeably.

Mast cell activation syndrome, also referred to as mast cell activation disorder (MCAD). An immunological condition. Wikipedia:Mast cell activation syndrome

Mast cell activation disorder, also known as mast cell activation syndrome (MCAS). An immunological condition. Wikipedia:Mast cell activation syndrome

Multiple Chemical Sensitivity is a chronic physical illness affecting people of all ages and backgrounds. It involves allergic-type reactions to very low levels of chemicals in everyday products and often also sensitivity to food, medicines, moulds and electromagnetic fields. A review of a two-phase population study of multiple chemical sensitivities

Multiple sclerosis (also known as disseminated sclerosis) is a chronic, typically progressive disease involving damage to the sheaths of nerve cells in the brain and spinal cord, whose symptoms may include numbness, impairment of speech and of muscular coordination, blurred vision and severe fatigue.